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Tecan HP D300

The HP D300e (originally HP, now distributed by Tecan) is a digital dispenser that uses inkjet technology to deliver picoliter volumes directly into destination plates. Disposable T8+ cassettes carry the compound or reagent; volumes are specified per well in software, no source plate required.

  • Digital dispense — well-by-well, volume specified per well
  • Dose-response curves — log-scale serial titrations generated automatically
  • Combinatorial layouts — multi-compound matrices in one cassette set
  • DMSO normalisation — top-up to a uniform DMSO concentration

Revolution drives the D300e via the D300e Control software API, dispatching protocols generated from Revolution’s compound/plate definitions. Cassettes must be primed and present on the deck before the run; the D300e reports back well-level dispense success.